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| Home | About and More Information | Transporter Data Index |
Synonyms: MATE1, RGD1311123
Entrez Gene Link
No expression data.
| Substrate | Km (μM) | Cell System | Reference |
|---|---|---|---|
| Paraquat | 170 | HEK293 cells | Chen, 2007 |
ND = not determined
1 denotes drugs that can potentially be used as in vitro substrates for studies of the transporter as defined by the FDA as of March 2022
2 denotes drugs that can potentially be used as in vitro inhibitors for studies of the transporter as defined by the FDA as of March 2022
3 denotes drugs that can potentially be used as clinical substrates for studies of the transporter as defined by the FDA as of March 2022
4 denotes drugs that can potentially be used as clinical inhibitors for studies of the transporter as defined by the FDA as of March 2022
| Inhibitor | IC50 (μM) | Ki (μM) | Substrate used | Cell System | Reference |
|---|---|---|---|---|---|
| Tetrabutylammonium | 13 | Paraquat | HEK293 cells | Chen, 2007 | |
| Tetraethylammonium | 153 | Paraquat | HEK293 cells | Chen, 2007 | |
| Tetramethylammonium | 5880 | Paraquat | HEK293 cells | Chen, 2007 | |
| Tetrapropylammonium | 42 | Paraquat | HEK293 cells | Chen, 2007 |
ND = not determined
1 denotes drugs that can potentially be used as in vitro substrates for studies of the transporter as defined by the FDA as of March 2022
2 denotes drugs that can potentially be used as in vitro inhibitors for studies of the transporter as defined by the FDA as of March 2022
3 denotes drugs that can potentially be used as clinical substrates for studies of the transporter as defined by the FDA as of March 2022
4 denotes drugs that can potentially be used as clinical inhibitors for studies of the transporter as defined by the FDA as of March 2022
No drug-drug interaction information.