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Implicated Transporter: OATs/MRPs

Interacting Drug: Probenecid
Dose Information: 2500 mg (total dose), 500 mg at -10 & -2 hrs & 500 mg at 4, 10 & 16 hours, oral

Affected Drug: Ciprofloxacin
Dose Information: 200 mg, single dose, IV infusion (30 min)

Study Design: Randomized crossover

References: Jaehde, 1995


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