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Valacyclovir

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
SLC15A1 PEPT1 5940 PEPT1-expressing oocytes Balimane, 1998
SLC15A1 PEPT1 1640 CHO-PEPT1 Guo, 1999

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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC15A1 PEPT1 Valacyclovir 910 Cefadroxil CHO-PEPT1 Guo, 1999
SLC15A1 PEPT1 Valacyclovir 4080 Glycylsarcosine PEPT1-expressing oocytes Balimane, 1998
SLC15A1 PEPT1 Valacyclovir 1280 Glycylsarcosine CHO-PEPT1 Guo, 1999

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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