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Tauroursodeoxycholate

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
SLCO1A2 OATP1A2, OATP-A 19 OATP1A2-expressing oocytes Kullak-Ublick, 1995
SLC10A1 NTCP 3.49 HEK-NTCP Maeda, 2006
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 7.47 HEK293-OATP1B1 Maeda, 2006
SLCO1B3 OATP1B3, OATP8 15.9 HEK293-OATP1B3 Maeda, 2006

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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC10A2 ASBT, SBAT2 Tauroursodeoxycholate 28 Taurocholate COS1-ASBT Craddock, 1998

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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