UCSF home page About UCSF UCSF Medical Center
UCSF home page | About UCSF | UCSF Medical Center

Skip to TransPortal content

Decrease the text sizeRestore original text sizeIncrease the text size
Transporter Database banner  
Decrease the text size | Restore text size | Increase the text size
 Text Sizer image
Home About and More Information Transporter Data Index
Search:  
 

Sorafenib

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 23.5 HEK-OATP1B1 Zimmerman, 2013

Back to top

In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A1 OCT1 Sorafenib 99 1-methyl-4-phenylpyridinium (MPP+) HEK293-OCT1 Johnston, 2014
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Sorafenib 0.0696 Docetaxel T-Rex293-OATP1B1 Hu, 2014
SLC22A1 OCT1 Sorafenib >30 Metformin HEK293-OCT1 Minematsu, 2011

Back to top

Clinical Drug-Drug Interactions

No drug-drug interaction information.


Back to top

Contact us | Glossary

Blue banner