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Pratosartan

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A12 URAT1 Pratosartan 0.0067 Uric acid URAT1-expressing oocytes Iwanaga, 2007
SLC22A11 OAT4 Pratosartan 31 Uric acid HEK293-OAT4 Sato, 2008
SLC22A6 OAT1 Pratosartan 1.5 Uric acid HEK293-OAT1 Sato, 2008
SLC22A8 OAT3 Pratosartan 0.095 Uric acid HEK293-OAT3 Sato, 2008

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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