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Pindolol

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A1 OCT1 Pindolol 39.1 1-methyl-4-phenylpyridinium (MPP+) HEK293-OCT1 Umehara, 2008
ABCC2 MRP2, cMOAT Pindolol >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC3 MRP3 Pindolol >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC4 MRP4 Pindolol >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCB11 BSEP Pindolol >133 Taurocholate Sf9 cell membrane vesicles Morgan, 2013
SLC22A1 OCT1 Pindolol 9.7 Tetraethylammonium HeLa-OCT1 Bednarczyk, 2003
ABCB1 MDR1, P-gp Pindolol 1950 Verapamil Caco-2 cells Doppenshmitt, 1998

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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