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N-butylpyridinium chloride (NBuPy-Cl)

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC47A1 MATE1 N-butylpyridinium chloride (NBuPy-Cl) 8.5 1-methyl-4-phenylpyridinium (MPP+) CHO-MATE1 Cheng, 2011
SLC47A2 MATE2K N-butylpyridinium chloride (NBuPy-Cl) 1.6 1-methyl-4-phenylpyridinium (MPP+) CHO-MATE2K Cheng, 2011
SLC22A2 OCT2 N-butylpyridinium chloride (NBuPy-Cl) 2.29 Tetraethylammonium CHO-OCT2 Cheng, 2011

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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