UCSF home page About UCSF UCSF Medical Center
UCSF home page | About UCSF | UCSF Medical Center

Skip to TransPortal content

Decrease the text sizeRestore original text sizeIncrease the text size Enlarge Text
Click to increase the text size. Restore Text
Click to restore original text size. Reduce Text
Click to decrease the text size.
Transporter Database banner  
Decrease the text size | Restore text size | Increase the text size
 Text Sizer image
Home About and More Information Transporter Data Index
Search:  
 

Leukotriene C4

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
ABCC1 MRP1 0.097 MRP1-expressing HeLa vesicles Leier, 1994
ABCC2 MRP2, cMOAT 1 MRP2-expressing MDCK vesicles Cui, 1999
ABCC2 MRP2, cMOAT 0.26 MRP2-expressing LLC PK1 vesicles Chen, 1999
ABCC3 MRP3 5.3 MRP3-expressing HEK293 vesicles Zeng, 2000
ABCC1 MRP1 0.167 MRP1-expressing HeLa vesicles Qian, 2001
ABCC1 MRP1 0.067 HeLa cell membrane vesicles Leslie, 2001
ABCC6 MRP6 0.6 MRP6-expressing Sf9 vesicles Ilias, 2002

Back to top

In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
ABCC2 MRP2, cMOAT Leukotriene C4 3.3 Para-aminohippurate MRP2-expressing HEK vesicles Leier, 2000

Back to top

Clinical Drug-Drug Interactions

No drug-drug interaction information.


Back to top

Contact us | Glossary

Blue banner