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Hydrocortisone

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
ABCB1 MDR1, P-gp Hydrocortisone >50 Calcein AM MDR1 expressing LLC-PK1 cells Schwab, 2003
mouse_Abcb1a Mdr, Pgp, Pgy, Mdr3, P-gp, Abcb4, Mdr1a Hydrocortisone >50 Calcein AM Mouse mdr1a expressing LLC-PK1 cells Schwab, 2003
mouse_Abcb1b mdr, Mdr1, Pgy1, Abcb1, Mdr1b, Pgy-1 Hydrocortisone >50 Calcein AM Mouse mdr1b expressing LLC-PK1 cells Schwab, 2003

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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