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Estradiol-17beta-glucuronide

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter

Transporter	Synonyms	Km (μM)	Cell System	Reference
ABCC1	MRP1	2.5	MRP1-expressing HeLa vesicles	Loe, 1996
ABCC1	MRP1	1.5	MRP1-expressing HeLa vesicles	Jedlitschky, 1996
ABCB1	MDR1, P-gp	62	MDR1-expressing Sf9 vesicles	Huang, 1998
ABCC1	MRP1	1.5	MRP1-expressing HEK293 vesicles	Cui, 1999
ABCC2	MRP2, cMOAT	7.2	MRP2-expressing HEK293 vesicles	Cui, 1999
ABCC2	MRP2, cMOAT	9.4	Caco-2 brush border membrane vesicles	Hirohashi, 2000
ABCC3	MRP3	25.6	MRP3-expressing HEK293 vesicles	Zeng, 2000
ABCC4	MRP4	30.3	MRP4-expressing Sf9 vesicles	Chen, 2001
ABCC3	MRP3	17.7	MRP3-expressing Sf9 vesicles	Zelcer, 2001
ABCG2	BCRP, MXR	44.2	BCRP-expressing HEK293 vesicles	Chen, 2003
ABCC3	MRP3	29	MRP3-expressing HEK293 vesicles	Zhang, 2003
SLCO1B1	OATP1B1, OATP-C, OATP2, LST-1	8.29	HEK293-OATP1B1	Hirano, 2004
SLCO1B3	OATP1B3, OATP8	24.6	HEK293-OATP1B1	Hirano, 2004
SLCO1B1	OATP1B1, OATP-C, OATP2, LST-1	2.5	HEK293-OATP1B1	Yamazaki, 2005
SLCO1B1	OATP1B1, OATP-C, OATP2, LST-1	5.4	CHO-OATP1B1	Gui, 2008
SLCO1B3	OATP1B3, OATP8	15.8	CHO-OATP1B3	Gui, 2008
SLCO1B1	OATP1B1, OATP-C, OATP2, LST-1	5.9	CHO-OATP1B1	Gui, 2009
SLCO1B1	OATP1B1, OATP-C, OATP2, LST-1	10	HEK-OATP1B1	Gozalpour, 2014

No inhibitor information.

No drug-drug interaction information.