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Chlorothiazide

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A11 OAT4 Chlorothiazide 2632 Estrone sulfate S2-OAT4 Hasannejad, 2004
SLC22A8 OAT3 Chlorothiazide 65.3 Estrone sulfate S2-OAT3 Hasannejad, 2004
SLC22A6 OAT1 Chlorothiazide 3.78 Para-aminohippurate S2-OAT1 Hasannejad, 2004
SLC22A7 OAT2 Chlorothiazide 2205 Prostaglandin F2-alpha S2-OAT2 Hasannejad, 2004

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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