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Cefoperazone

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Km (μM) Cell System Reference
SLCO1B3 OATP1B3, OATP8 1.95 oocytes-OATP1B3 Nakakariya, 2008
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 4.84 OATP1B1-expressing oocytes Nakakariya, 2008

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In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLC22A11 OAT4 Cefoperazone 2800 Prostaglandin F2-alpha S2-OAT4 Khamdang, 2003
SLC22A6 OAT1 Cefoperazone 210 Prostaglandin F2-alpha S2-OAT1 Khamdang, 2003
SLC22A7 OAT2 Cefoperazone 1330 Prostaglandin F2-alpha S2-OAT2 Khamdang, 2003
SLC22A8 OAT3 Cefoperazone 1890 Prostaglandin F2-alpha S2-OAT3 Khamdang, 2003

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Clinical Drug-Drug Interactions

No drug-drug interaction information.


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