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Cefadroxil

In Vitro Substrates

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter

Transporter	Synonyms	Km (μM)	Cell System	Reference
SLC15A1	PEPT1	ND	HeLa-PEPT1	Knutter, 2009
SLCO1B3	OATP1B3, OATP8	4.15	oocytes-OATP1B3	Nakakariya, 2008

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter

Transporter	Synonyms	Inhibitor	IC50 (μM)	Ki (μM)	Substrate used	Cell System	Reference
ABCC2	MRP2, cMOAT	Cefadroxil	>133		Estradiol-17beta-glucuronide	Sf9 cell membrane vesicles	Morgan, 2013
ABCC3	MRP3	Cefadroxil	>133		Estradiol-17beta-glucuronide	Sf9 cell membrane vesicles	Morgan, 2013
ABCC4	MRP4	Cefadroxil	>133		Estradiol-17beta-glucuronide	Sf9 cell membrane vesicles	Morgan, 2013
SLC22A6	OAT1	Cefadroxil		6140	Prostaglandin F2-alpha	S2-OAT1	Khamdang, 2003
SLC22A8	OAT3	Cefadroxil		8620	Prostaglandin F2-alpha	S2-OAT3	Khamdang, 2003
ABCB11	BSEP	Cefadroxil	>133		Taurocholate	Sf9 cell membrane vesicles	Morgan, 2013

No drug-drug interaction information.