UCSF home page About UCSF UCSF Medical Center
UCSF home page | About UCSF | UCSF Medical Center

Skip to TransPortal content

Decrease the text sizeRestore original text sizeIncrease the text size
Transporter Database banner  
Decrease the text size | Restore text size | Increase the text size
 Text Sizer image
Home About and More Information Transporter Data Index
Search:  
 

Amlodipine

Substrate Information
Inhibitor Information
Clinical Drug-drug Interactions

In Vitro Substrates

No substrate information.


Back to top

In Vitro Inhibitors

* denotes drugs that can potentially be used for in vivo (clinical) studies of the designated transporter
Transporter Synonyms Inhibitor IC50 (μM) Ki (μM) Substrate used Cell System Reference
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Amlodipine 35.5 Cerivastatin HEK-OATP1B1 Tamraz, 2013
ABCB1 MDR1, P-gp Amlodipine 22 Daunorubicin MDR1 expressing LLC-PK1 cells Katoh, 2000
ABCC2 MRP2, cMOAT Amlodipine >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC3 MRP3 Amlodipine >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
ABCC4 MRP4 Amlodipine >133 Estradiol-17beta-glucuronide Sf9 cell membrane vesicles Morgan, 2013
SLCO1B1 OATP1B1, OATP-C, OATP2, LST-1 Amlodipine 39.6 Estrone sulfate HEK-OATP1B1 Tamraz, 2013
SLC22A5 OCTN2 Amlodipine 96 L-carnitine MDCKII-hOCTN2 Diao, 2009
ABCB11 BSEP Amlodipine >133 Taurocholate Sf9 cell membrane vesicles Morgan, 2013

Back to top

Clinical Drug-Drug Interactions

No drug-drug interaction information.


Back to top

Contact us | Glossary

Blue banner